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Toxicological reference values (TRVs) set by the JMPR
| TRV | Value | Reference | Comments |
|---|---|---|---|
| ADI | 0.01 mg/kg bw per day | FAO and WHO (1995) | Based on the overall NOAEL of 1.2 mg/kg bw per day seen in several carcinogenicity studies in rats and applying an UF of 100 |
| ARfD | – | – | Not considered at the time of the assessment |
ADI: acceptable daily intake; ARfD: acute reference dose; bw: body weight; NOAEL: no observed adverse effect level; UF: uncertainty factor.
