Table 2.
Characteristics of the longitudinal S-Factor cohort
| SCA1 (N=54) | SCA2 (N=56) | SCA3 (N=121) | SCA6 (N=50) | Overall (N=281) | |
|---|---|---|---|---|---|
| Baseline age | 49.2 (10.6), [25.4, 68.9] | 47.0 (12.3), [14.5, 67.4] | 49.9 (11.0), [19.6, 73.5] | 62.4 (10.3), [31.2, 80.2] | 51.4 (12.2), [14.5, 80.2] |
| Gender (female;male) | 32;22 | 32;24 | 59;62 | 29;21 | 152;129 |
| Baseline total SARA score | 9.68 (5.25), [1.00, 28.5] | 14.6 (5.27), [5.50, 28.0] | 11.2 (7.64), [0.500, 33.0] | 12.9 (7.09), [2.00, 32.0] | 11.9 (6.88), [0.500, 33.0] |
| Age at disease onset | 41.4 (10.2), [24.0, 65.0] | 36.7 (12.1), [4.00, 62.0] | 40.3 (11.6), [15.0, 68.0] | 52.8 (10.5), [25.0, 70.0] | 42.0 (12.4), [4.00, 70.0] |
| Baseline disease duration | 7.73 (5.12), [0.0100, 25.0] | 10.3 (6.03), [0.320, 26.9] | 9.56 (8.72), [0, 48.2] | 9.56 (9.58), [0.500, 43.1] | 9.36 (7.84), [0, 48.2] |
| CAG expansion repeat length | 46.4 (3.68), [41.0, 56.0] | 39.9 (4.12), [34.0, 60.0] | 71.6 (4.01), [60.0, 81.0] | 22.4 (0.942), [21.0, 26.0] | 51.7 (19.2), [21.0, 81.0] |
| Number of visits with a SARA assessment | 3.17 (1.34), [2.00, 7.00] | 2.98 (1.00), [2.00, 5.00] | 3.24 (1.29), [2.00, 9.00] | 3.34 (1.26), [2.00, 7.00] | 3.19 (1.24), [2.00, 9.00] |
| Duration of follow-up | 2.57 (2.74), [0.364, 11.1] | 2.19 (2.22), [0.460, 9.27] | 2.12 (2.16), [0.384, 10.7] | 2.34 (2.50), [0.499, 9.95] | 2.26 (2.34), [0.364, 11.1] |
Mean (standard deviation), [range]