Figure 3.
Alterations in HPA axis hormones and proteins. Plasma concentrations of ACTH (A), total cortisol (B), CBG (C), albumin (D) and free cortisol (E). (A) The dotted line represents the threshold for low ACTH levels of 10 pg/ml. (A-F) Each symbol represents data from an individual. (A-E) Horizontal lines in between data points represent group medians and analysis was by Mann-Whitney U-test. Asterisks above individual data sets indicate statistical differences compared to the AC group. Horizontal lines with asterisks on top indicate the levels of statistical significance between the indicated groups.* p<0.05, ** p<0.01, *** p<0.001. (F) Correlation between free cortisol and ACTH. Spearman r- and p-values are shown. Only significant differences are indicated. AC n=23; UM n=21; SM n=26.
