Figure 1.

Graphical depiction of the association of maternal age at birth (A), gestational age (B), birth weight (C), and age at initial TBI (D), respectively, with the risk of anxiety as estimated by modelling each covariate using a smoothing spline in a separate Cox model. The dashed lines denote 95% confidence bands for the hazard ratio (HR). For illustrative purposes the values in the tails of the distribution of each covariate have been rounded prior to fitting the Cox models. Each graph was generated such that the reference point with a HR of 1.0 was set at the mean of each covariate.