Table 1.
Cytokines and growth factors (pg/ml) released following 24 and 48 h of triclosan exposure on EpiDerm.
Exposure Duration Triclosan (w/v) | 24h |
48h |
||||||
---|---|---|---|---|---|---|---|---|
0% | 0.05% | 0.1% | 0.2% | 0% | 0.05% | 0.1% | 0.2% | |
IL-1α | 19.4 ± 2.2 | 29.3 ± 3.6 | *39.7 ± 2.8 | *54.0 ± 9.1 | 26.2 ± 11.1 | 32.4 ± 11.9 | *61.0 ± 26.2 | *71.8 ± 14.7 |
IL-36 | 49.5 ± 3.2 | 59.1 ± 3.3 | *70.4 ± 10.7 | *99.3 ± 6.0 | 78.7 ± 9.8 | 84.1 ± 5.8 | *114.3 ± 9.8 | *145.9 ± 19.3 |
CXCL8 | 72.7 ± 7.7 | 54.5 ± 1.5 | 59.9 ± 6.2 | 46.9 ± 5.6 | 100.4 ± 38.3 | 93.8 ± 29.0 | 115.7 ± 54.7 | 66.3 ± 25.8 |
VEGF | 79.8 ± 20.6 | *102.0 ± 20.9 | *121.2 ± 18.4 | *129.1 ± 9.6 | 112.8 ± 32.7 | 136.2 ± 27.0 | *154.0 ± 27.8 | 142.7 ± 38.0 |
EGF | 28.5 ± 21.1 | 31.0 ± 19.9 | 28.6 ± 19.0 | 31.7 ± 22.7 | 39.6 ± 3.8 | 44.1 ± 0.3 | 42.9 ± 6.0 | 43.4 ± 3.6 |
Numbers represent mean (± SEM) of two samples/group. *p < 0.05 vs. 0% triclosan.