Table 2.
Cytokines and growth factors (pg/ml) released following 5 days of triclosan exposure on EpiDerm.
| Cytokine | Triclosan (w/v) | 1 Day | 2 Days | 3 Days | 4 Days | 5 Days |
|---|---|---|---|---|---|---|
| IL-1α | 0% | 74.3 ± 12.9 | 94.2 ± 33.6 | 136.8 ± 10.7 | 140.6 ±13.8 | 163.2 ± 29.8 |
| 0.1% | *181.9 ± 98.0 | 167.9 ± 78.5 | 211.9 ± 9.7 | 200.2 ± 8.7 | 186.8 ± 27.4 | |
| 0.2% | *254.0 ± 119.8 | *198.5 ± 74.5 | 249.9 ± 10.0 | 184.6 ± 21.9 | 154.3 ± 30.7 | |
| IL-36 | 0% | 127.3 ± 80.8 | 74.8 ± 53.4 | 59.5 ± 30.7 | 51.6 ± 26.9 | 50.1 ± 21.4 |
| 0.1% | 240.1 ± 157.8 | 179.5 ± 107.2 | *211.7 ± 38.0 | *218.4 ± 23.3 | *222.9 ± 42.0 | |
| 0.2% | *371.0 ± 243.0 | *236.2 ± 126.7 | *298.2 ± 45.3 | *257.4 ± 45.7 | *212.1 ± 50.8 | |
| CXCL8 | 0% | 332.2 ± 188.3 | 230.7 ± 100.0 | 269.7 ± 20.8 | 246.9 ± 29.5 | 243.2 ± 30.0 |
| 0.1% | 372.9 ± 237.9 | 181.5 ± 93.4 | 127.0 ± 8.4 | 71.0 ± 4.1 | *42.5 ± 3.0 | |
| 0.2% | 361.0 ± 240.4 | 152.6 ± 88.4 | 88.6 ± 13.5 | *43.7 ± 1.7 | *27.2 ± 0.9 | |
| VEGF | 0% | 336.6 ± 115.9 | 274.0 ± 129.9 | 40.8 | 310.8 ± 45.5 | 326.8 ± 74.3 |
| 0.1% | 563.8 ± 203.9 | 456.0 ± 205.0 | 487.0 ± 110.5 | 302.4 ± 139.2 | *186.5 ± 130.3 | |
| 0.2% | 498.3 ± 224.1 | 312.9 ± 165.3 | *178.9 ± 47.0 | *68.5 ± 19.5 | *38.9 ± 13.3 | |
| EGF | 0% | 21.2 ± 3.9 | 17.9 ± 6.8 | 22.6 ± 0.9 | 23.0 ± 1.3 | 21.4 ± 2.4 |
| 0.1% | 24.0 ± 9.1 | 22.7 ± 9.5 | 33.1 ± 0.1 | *40.1 ± 1.6 | *44.2 ± 3.2 | |
| 0.2% | 25.2 ± 10.2 | 30.2 ± 11.4 | *48.7 ± 3.5 | *54.3 ± 7.1 | *56.6 ± 10.8 |
Numbers represent mean (± SEM) of two samples/group. *p < 0.05 vs. 0%.