Supplementary Table-III.
Sensitivity analysis of the effect estimate of each outcome by toggling through each included study.
| Outcomes | Studies included | Change in significance of RR | ||
|---|---|---|---|---|
| 1 | Comparison of outcomes between Inadequate GWG versus Adequate GWG in twin mothers | |||
| 1.1 | Maternal Outcomes | |||
| 1.1.1 | Gestational Diabetes | 9 | Removing other studies | No Major Change |
| Removing Liu et al. 2021 | 1.30 [1.01, 1.66], p=0.04 | |||
| 1.1.2 | Gestational Hypertension | 12 | Removing each study | No Major Change |
| 1.1.3 | Caesarean Delivery | 8 | Removing Other studies | No Major Change |
| Removing Bodnar et al. 2020 | 0.97 [0.92, 1.03], p=0.37 | |||
| Removing Choi et al. 2020 | 0.97 [0.92, 1.02], p=0.23 | |||
| Removing Shimura et al. 2020 | 0.95 [0.93, 0.96], p<0.0001 | |||
| 1.1.4 | Post-partum haemorrhage | 3 | Removing each study | No Major Change |
| 1.1.5 | Premature rupture of membrane | 6 | Removing other studies | No Major Change |
| Removing Lin et al. 2019 | 1.15 [1.00, 1.33], p=0.05 | |||
| 1.2 | Neonatal Outcomes | |||
| 1.2.1 | Pre-term birth <37 weeks | 10 | Removing each study | No Major Change |
| 1.2.2 | Pre-term birth <32 weeks | 8 | Removing other studies | No Major Change |
| Removing Liu et al. 2021 | 1.87 [1.40, 2.50], p<0.0001 | |||
| 1.2.3 | Small at Gestational Age | 12 | Removing each study | No Major Change |
| 1.2.4 | Low birth weight <2500gm | 6 | Removing each study | No Major Change |
| 1.2.5 | Admission to NICU | 6 | Removing each study | No Major Change |
| 2 | Comparison of outcomes between Excessive GWG versus Adequate GWG in twin mothers | |||
| 2.1 | Maternal Outcomes | |||
| 2.1.1 | Gestational Diabetes | 9 | Removing other studies | No Major Change |
| Removing Pecheux et al. 2019 | 0.78 [0.64, 0.95], p<0.01 | |||
| 2.1.2 | Gestational Hypertension | 12 | Removing each study | No Major Change |
| 2.1.3 | Caesarean Delivery | 8 | Removing Other studies | No Major Change |
| Removing Bodnar et al. 2020 | 1.05 [1.02, 1.08], p=0.0004 | |||
| 2.1.4 | Post-partum haemorrhage | 3 | Removing each study | No Major Change |
| 2.1.5 | Premature rupture of membrane | 7 | Removing each study | No Major Change |
| 2.2 | Neonatal Outcomes | |||
| 2.2.1 | Pre-term birth <37 weeks | 9 | Removing each study | No Major Change |
| 2.2.2 | Pre-term birth <32 weeks | 9 | Removing each study | No Major Change |
| 2.2.3 | Small at Gestational Age | 12 | Removing each study | No Major Change |
| 2.2.4 | Low birth weight <2500gm | 7 | Removing each study | No Major Change |
| 2.2.5 | Admission to NICU | 6 | Removing each study | No Major Change |