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Univariate (top) and two-way interactive (bottom) predictors of cognitive subgroups; features are listed in descending order according to mutual information criterion (MIC), a metric that describes the relative contribution of each feature to the model; interaction terms capture both linear and nonlinear combinations (see Online Resources 3 and 4); results suggest prominent contributions of brain volumetrics, demographics, and substance use in the delineation of cognitive subgroups
