Table 2.

Performance of MRI and PET–CT for the prediction of pCR at the time of surgery

	Breast MRI (n = 47*)	PET–CT (n = 45†)
Accuracy (%)	77 (62, 88)	78 (63, 89)
Sensitivity (%)	77 (55, 92)	50 (27, 73)
Specificity (%)	76 (55, 91)	100 (86, 100)
False-negative rate (1 – sensitivity) (%)	23 (8, 45)	50 (27, 73)
False-positive rate (1 – specificity) (%)	24 (9, 45)	0
Positive predictive value (%)	74 (52, 90)	100 (69, 100)
Negative predictive value (%)	79 (58, 93)	71 (54, 85)

Values in parentheses are 95% exact confidence intervals. The analysis included 50 patients: 22 with an imaging complete response (2 with residual disease at vacuum-assisted breast biopsy (VABB) and 20 with a complete response at VABB included in primary analysis) and 28 with residual disease at postneoadjuvant therapy imaging. *Three patients had missing information on MRI. †Five patients had missing information on PET.