Table 1.
Baseline characteristics of patients with pathologically confirmed perihilar cholangiocarcinoma
| No. of patients (n = 1673)* | |
|---|---|
| Sex ratio (M : F) | 962 : 711 |
| Age (years), median (i.q.r.) | 65 (56–72) |
| ≥70 | 481 (33.3) |
| BMI (kg/m2), median (i.q.r.) | 24.9 (22.4–27.3) |
| WHO grade | |
| ȃ0 | 371 (54.2) |
| ȃ1 | 258 (37.7) |
| ȃ2 | 51 (7.4) |
| ȃ3 | 5 (0.7) |
| Jaundice at presentation | 1260 (79.5) |
| ASA fitness grade | |
| ȃI–II | 942 (62.5) |
| ȃIII–IV | 565 (37.5) |
| Primary sclerosing cholangitis | 47 (4.0) |
| Preoperative biliary drainage | 1389 (83.1) |
| Preoperative cholangitis | 338 (22.3) |
| Bismuth–Corlette classification | |
| ȃI–III | 1210 (73.5) |
| ȃIV | 437 (26.5) |
| Portal vein invasion† | 428 (40.3) |
| Hepatic artery invasion† | 259 (24.5) |
| Tumor diameter (cm), median (i.q.r.) | 2.7 (2.0–4.0) |
| Portal vein embolization | 131 (16.1) |
| Surgery | |
| ȃLeft hemihepatectomy | 523 (31.3) |
| ȃLeft extended hemihepatectomy | 273 (16.3) |
| ȃRight Hemihepatectomy | 307 (18.4) |
| ȃRight extended hemihepatectomy | 570 (34.1) |
| Portal vein reconstruction | 529 (33.4) |
| Hepatic artery reconstruction | 54 (3.4) |
| Pancreatoduodenectomy | 22 (1.5) |
| R1 resection margin | 553 (33.3) |
| AJCC T category‡ | |
| ȃT1–2 | 1052 (64.6) |
| ȃT3–4 | 577 (35.4) |
| Lymph node metastases | |
| ȃN0 | 929 (56.8) |
| ȃN1 | 663 (40.6) |
| ȃN2 | 40 (2.4) |
| Poor tumour differentation | 376 (24.5) |
| Perineural invasion | 1113 (77.0) |
*Values are n (%) unless indicated otherwise. †Portal vein or hepatic artery invasion was defined as tumour contact of at least 180° on imaging. ‡AJCC 7th edition. T1–2: Bismuth type 1–3 without any vascular involvement.