Table 3.
Univariable and multivariable survival analyses of factors associated with overall survival of patients with perihilar cholangiocarcinoma
| Univariable analysis | Multivariable analysis | |||
|---|---|---|---|---|
| HR | P | HR | P | |
| Male sex | 1.16 (1.03, 1.30) | 0.016 | ||
| Age (years) | 1.01 (1.00, 1.01) | 0.025 | 1.01 (1.00, 1.01) | 0.115 |
| BMI (kg/m2) | 1.02 (1.00, 1.03) | 0.060 | 1.02 (1.00, 1.03) | 0.022 |
| Jaundice at presentation | 1.52 (1.30, 1.78) | <0.001 | 1.43 (1.21, 1.69) | <0.001 |
| ASA grade III–IV | 1.39 (1.23, 1.58) | <0.001 | 1.34 (1.17, 1.54) | <0.001 |
| Primary sclerosing cholangitis | 0.95 (0.67, 1.34) | 0.754 | ||
| Preoperative biliary drainage | 1.21 (1.03, 1.42) | 0.021 | ||
| Preoperative cholangitis | 1.19 (1.02, 1.37) | 0.025 | 1.16 (0.99, 1.36) | 0.069 |
| Bismuth type IV | 1.23 (1.08, 1.41) | 0.001 | 1.20 (1.05, 1.37) | 0.009 |
| Hepatic artery involvement | 1.36 (1.14, 1.62) | <0.001 | 1.27 (1.09, 1.50) | 0.002 |
| Tumour diameter (cm) | 1.02 (1.01, 1.03) | <0.001 | 1.02 (1.00, 1.03) | 0.013 |
| Right-sided hepatectomy | 1.26 (1.12, 1.42) | <0.001 | 1.27 (1.13, 1.44) | <0.001 |
| Extended hepatectomy | 1.26 (1.12, 1.42) | <0.001 | ||
| C-index for model | 0.601 | |||
Values in parentheses are 95% confidence intervals.