Table 6.
Subgroup and meta-regression analysis for superparamagnetic iron oxide nanoparticle-induced skin staining
| Skin staining (%) | Coefficient b | P | |
|---|---|---|---|
| Injection volume (ml) | −0.0061 (−0.0816, 0.0693)* | 0.863 | |
| ȃ0.5 | 0 (0, 19.9) | ||
| ȃ1.0 | 25.2 (9.4, 41.0) | ||
| ȃ1.5 | 43.3 (37.0, 49.5) | ||
| ȃ2.0 | 32.1 (26.9, 37.2) | ||
| ȃ5.0 | 31.3 (20.5, 42.1) | ||
| Injection site | 0.2390 (−0.2178, 0.6958)† | 0.279 | |
| ȃSubareolar | 36.6 (25.8, 47.3) | ||
| ȃPeritumoral | 15.4 (0, 36.2) | ||
| Massage | 0.0344 (–0.4202, 0.4891)‡ | 0.873 | |
| ȃYes | 34.7 (22.7, 46.6) | ||
| ȃNo | 24.4 (6.3, 42.6) |
Values in parentheses are 95% confidence intervals. Coefficient for *lower superparamagnetic iron oxide nanoparticle volume, †subareolar injection or ‡perioperative injection with massage.