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. 2022 Nov 4;110(1):67–75. doi: 10.1093/bjs/znac350

Table 4.

Histological features in pancreatic cancer resections that pathologists identified as indicative of treatment effect

No. of pathologists
Stromal changes
 Mucin pools 10 of 18
 Fibro(myxoid) changes 8 of 18
 Foamy cells 3 of 18
 Histiocytes 1 of 18
Cellular changes
 Cellular degenerative changes 9 of 18
 Cytoplasmic vacuolization 4 of 18
 Nuclear atypia 5 of 18
 Clear cell change 4 of 18
General changes
 Reduced cancer cell density 10 of 18
 Vascular changes 5 of 18
 Necrosis 2 of 18
Others
 Duodenal protection from treatment effect 2 of 18
 Islet hyperplasia 1 of 18
 Neural hyperplasia 1 of 18
 Tumour insular complexes 1 of 18
 Duct destruction 1 of 18
 Parenchymal congestion 1 of 18