Table 2.
Univariate and multivariate analyses in the study cohort.
| Variables | Univariate analysis |
Multivariate analysis |
|||||
|---|---|---|---|---|---|---|---|
| HR | 95% CI | p value | β | HR | 95% CI | p value | |
| Age (>53 y) | 3.566 | 1.573–8.088 | 0.003 | 1.171 | 3.225 | 1.106–9.408 | 0.032 |
| FIB (>4.3 g/L) | 0.271 | 0.115–0.639 | 0.002 | ||||
| ALT (>92.4 U/L) | 7.275 | 2.883–18.356 | <0.001 | ||||
| AST (>86.5 U/L) | 8.281 | 3.289–20.850 | <0.001 | 1.368 | 3.929 | 1.220–12.655 | 0.022 |
| ALP (>150.9 U/L) | 3.872 | 1.674–8.959 | 0.002 | 1.671 | 5.317 | 1.506–18.772 | 0.009 |
| LDH (>733 U/L) | 2.687 | 1.161–6.217 | 0.035 | ||||
| CK (>42.7 U/L) | 3.064 | 1.170–8.025 | 0.022 | ||||
| TB (>27.3 μmol/L | 3.594 | 1.543–8.371 | 0.004 | ||||
| DB (>17.3 μmol/L) | 4.959 | 2.025–12.146 | 0.001 | ||||
| TG (<4.69 mmol/L) | 0.118 | 0.015–0.907 | 0.016 | −2.179 | 0.113 | 0.012–0.999 | 0.049 |
| UREA (>9.67 mmol/L) | 5.568 | 2.335–13.276 | <0.001 | ||||
| CREA (>79.4 μmol/L) | 8.131 | 3.208–20.607 | <0.001 | 2.163 | 8.694 | 2.665–28.361 | <0.001 |
| AUC | 0.875 | ||||||
ALP: alkaline phosphatase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; AUC: area under the cure; CI: confidence interval; CK: creatine kinase; CREA: creatinine; DB: direct bilirubin; FIB: fibrinogen; HR: hazard ratio; LDH: lactate dehydrogenase; TB: total bilirubin; TG: triglycerides; UREA: urea nitrogen; β: regression coefficient.