Figure 3.

Effects of genotype, sex, and treatment—vehicle compared to FPT—on relative EEG power in male and female WT and Fmr1 KO mice. For clarity, only significant (P < 0.05) main effects are written on the graphs. Notably, FPT significantly increased relative delta and beta power recorded above the somatosensory cortices and decreased relative alpha power recorded above the somatosensory and auditory cortices. FPT decreased relative gamma power in the right somatosensory cortex in most groups. Note also that where FPT had significant effects, they tended to be more robust in Fmr1 KO than in WT mice. Data were analyzed by repeated measures three-way ANOVA. Results from Fisher’s LSD multiple comparisons tests are reported in the Results section.