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. 2023 Jul 10;13:1106281. doi: 10.3389/fonc.2023.1106281

Table 1.

The clinical and laboratory characteristics of PHNET and NBNC-HCC in the study.

Variable PHNET (n=14) NBNC-HCC (n=28) P value
Age (range, year) 56.9 ± 12.2 (32-74) 58.5± 10.4 (40-78) 0.984
Sex 0.040
Male 6 (42.9%) 21 (75.0%)
Female 8 (57.1%) 7 (25.0%)
Chronic hepatitis B 2 (14.3%) 0 (0.0%) 0.106
Chronic hepatitis C 0 (0.0%) 0 (0.0%)
Fatty liver disease 1 (7.1%) 6 (21.4%) 0.242
AFP (ng/ml) 0.111
≤ 20 13 (92.9%) 20 (71.4%)
> 20 1 (7.1%) 8 (28.6%)
CA 19-9 (U/ml) 0.350
≤ 30 11 (78.6%) 25 (89.3%)
> 30 3 (21.4%) 3 (10.7%)
CEA (ng/ml) 0.457
≤ 5 12 (85.7%) 26 (92.9%)
> 5 2 (14.3%) 2 (7.1%)
ALT (IU/L) 0.798
≤ 40 11 (78.6%) 21 (75.0%)
> 40 3 (21.4%) 7 (25.0%)
Total bilirubin (umol/L) 0.500
≤ 28 13 (92.9%) 24 (85.7%)
> 28 1 (7.1%) 4 (14.3%)
Albumin (g/L) 0.545
≤ 40 0 (0.0%) 2 (7.1%)
> 40 14 (100.0%) 26 (92.9%)

PHNET, primary hepatic neuroendocrine tumors. NBNC-HCC, hepatocellular carcinoma with negative for hepatitis B virus surface antigen and hepatitis C antibody; AFP, alpha-fetoprotein; CA 19-9, carbohydrate antigen 19-9; CEA, carcinoembryonic antigen. Unless otherwise stated, data are numbers of patients, with percentage in parentheses.