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. 2023 Jul 10;13:1106281. doi: 10.3389/fonc.2023.1106281

Table 2.

The comparison of conventional ultrasound features between PHNET and NBNC-HCC.

Variable PHNET (n=14) NBNC-HCC (n=28) P value
Location 0.637
Right liver 9 (64.3%) 20 (71.4%)
Left liver 5 (35.7%) 8 (28.6%)
Tumor size (range, cm) 10.1 ± 4.7 (2.0-14.4) 5.9 ± 3.8 (1.5-17.0) 0.006
Tumor number 0.770
Solitary 12 (85.7%) 23 (82.1%)
Multiple 2 (14.3%) 5 (17.9%)
Morphology 0.513
Regular 6 (42.9%) 15 (53.6%)
Irregular 8 (57.1%) 13 (46.4%)
Tumor borders 0.827
Well-defined 7 (50.0%) 13 (46.4%)
Ill-defined 7 (50.0%) 15 (53.6%)
Echogenicity 0.001
Hypoechoic 6 (42.9%) 25 (89.3%)
Hyperechoic 4 (28.6%) 3 (10.7%)
Mixed echoic 4 (28.6%) 0
Lesions with calcification 3 (21.4%) 0 0.034
Color Doppler signal 0.798
rare 11 (78.6%) 21 (75.0%)
rich 3 (21.4%) 7 (25.0%)
Tumor in vein 0 1 (3.6%) 0.474
Liver background 0.710
Homogeneous 13 (92.9%) 25 (89.3%)
Heterogeneous 1 (7.1%) 3(10.7%)

PHNET, primary hepatic neuroendocrine tumors; NBNC-HCC, hepatocellular carcinoma with negative for hepatitis B virus surface antigen and hepatitis C antibody. Unless otherwise stated, data are numbers of patients, with percentage in parentheses.