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. 2023 Jul 10;14:1223312. doi: 10.3389/fendo.2023.1223312

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Copyright © 2023 Sekhar, Codreanu, Williams, Rathmell, Rathmell, McLean, Sherrod and Baregamian

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Experimental Design. (A) The workflow for the benign parathyroid tissue and tissue matched FNA-derived parathyroid organoid metabolic analyses. (B) The workflow for metabolomic analysis of parathyroid organoids and tissues using UHPLC/MS/MS. (C) The workflow for bioenergetic studies of organoids using the Agilent Seahorse Analyzer XF platform. (D) The workflow for the cryopreserved parathyroid organoid hormone production assessment by ELISA.