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. 2022 Apr 5;109(6):530–538. doi: 10.1093/bjs/znac077

Table 5.

Exploratory univariable logistic regression of risk factors for complications

Implant loss Readmission Reoperation Infection
Odds ratio P Odds ratio P Odds ratio P Odds ratio P
Age (per year) 1.04 (1.00, 1.07) 0.053 1.02 (1.00, 1.05) 0.090 1.04 (1.01, 1.07) 0.010 1.02 (0.99, 1.04) 0.229
Obesity (BMI ≥ 30 kg/m2) 1.03 (0.40, 2.65) 0.949 1.05 (0.53, 2.08) 0.882 0.93 (0.45, 1.92) 0.849 0.89 (0.45, 1.74) 0.727
Current smoking/nicotine use 1.75 (0.62, 4.90) 0.288 2.49 (1.20, 5.15) 0.014 2.18 (1.02, 4.68) 0.045 2.41 (1.18, 4.90) 0.015
Previous radiotherapy 4.53 (1.63, 12.61) 0.004 1.29 (0.46, 3.58) 0.632 2.26 (0.89, 5.73) 0.085 2.16 (0.89, 5.25) 0.090
Neoadjuvant chemotherapy 1.33 (0.47, 3.76) 0.586 0.47 (0.18, 1.25) 0.132 0.56 (0.21, 1.49) 0.244 0.73 (0.32, 1.66) 0.452
Bilateral surgery 0.65 (0.24, 1.76) 0.393 0.64 (0.32, 1.30) 0.220 0.64 (0.31, 1.33) 0.233 1.06 (0.57, 1.95) 0.863
At least one mastectomy for malignancy 0.83 (0.27, 2.51) 0.741 1.32 (0.53, 3.30) 0.549 0.96 (0.40, 2.28) 0.919 1.04 (0.46, 2.37) 0.917
Biological mesh 2.62 (0.34, 20.03) 0.354 3.19 (0.74, 13.8) 0.121 1.26 (0.42, 3.77) 0.681 0.74 (0.08, 7.28) 0.799
Duration of operation (per min) 1.00 (0.99, 1.01) 0.629 1.00 (1.00, 1.01) 0.666 1.00 (0.99, 1.01) 0.846 1.00 (0.99, 1.00) 0.500
Anticipated large implant (≥ 600 ml) 3.20 (0.98, 10.48) 0.055 1.71 (0.59, 4.95) 0.321 2.32 (0.85, 6.38) 0.102 2.56 (0.97, 6.75) 0.058
At least one nipple-sparing procedure (versus other mastectomy patterns) 1.77 (0.77, 4.10) 0.181 1.13 (0.64, 1.99) 0.674 1.21 (0.69, 2.18) 0.532 1.24 (0.72, 2.13) 0.444
Good skin-flap vascularity (versus average or poor) 2.07 (0.88, 4.88) 0.094 2.07 (1.11, 3.86) 0.023 2.18 (1.15, 4.14) 0.017 1.25 (0.66, 2.37) 0.486
Mastectomy weight ≤ 600 g (versus > 600 g) 2.34 (1.01, 5.41) 0.047 1.37 (0.71, 2.65) 0.350 2.01 (1.05, 3.88) 0.036 1.55 (0.83, 2.89) 0.170
Considered as being at moderate/high risk of complications before surgery* 3.58 (1.54, 8.31) 0.003 1.05 (0.59, 1.89) 0.867 1.82 (1.00, 3.28) 0.049 0.95 (0.54, 1.67) 0.849

Values in parentheses are 95 per cent confidence intervals. *At least one risk factor from: high BMI, current smoking, previous radiotherapy, anticipated postmastectomy radiotherapy, anticipated implant volume exceeding 600 ml; or considered high risk by operating surgeon for another reason.