Table 3.
Pooled outcomes after endoscopic vacuum therapy in patients with pelvic anastomotic leakage
| Total | No ESC | ESC | |||||||
|---|---|---|---|---|---|---|---|---|---|
| No. of studies | n | Pooled value (%)* | No. of studies | n | Pooled value (%)* | No. of studies | n | Pooled value (%)* | |
| Interval from surgery to AL diagnosis (days) | 16 | 272 | 20.2 (15.9, 24.6)† | 12 | 198 | 23.5 (17.2, 29.9)† | 3 | 54 | 15 (8.3, 22.5)† |
| Interval from surgery to EVT (days) | 15 | 265 | 35.9 (27.8, 44.0)† | 11 | 191 | 38.3 (28.8, 47.8)† | 3 | 54 | 23 (9.1, 37.0)† |
| No. of sponges used | 26 | 710 | 9.1 (7.0, 11.3)† | 22 | 636 | 9.8 (7.3, 12.3)† | 3 | 54 | 4 (2.7, 4.6)† |
| Anastomotic function | |||||||||
| Restored continuity (%) | 22 | 578 | 66.8 (58.8, 73.9) | 18 | 505 | 64.7 (55.7, 72.7) | 3 | 54 | 82.0 (50.1, 95.4) |
| Time to restored continuity (months)‡ | 7 | 114 | 5.1 (3.3, 6.9)† | 3 | 51 | 4 (2.5, 4.9)† | 3 | 43 | 2 (0.9, 4.0)† |
| Complications | |||||||||
| Procedure-related | 25 | 516 | 6.7 (4.7, 9.6) | 22 | 461 | 10.2 (6.7, 15.1) | 2 | 48 | 2 (0, 0.1) |
| Late (during follow-up) | 21 | 440 | 10.8 (6.8, 16.7) | 18 | 372 | 9.7 (6.0, 15.3) | 2 | 48 | 14 (1.0, 72.3) |
Values in parentheses are 95 per cent confidence intervals. *Unless indicated otherwise; †mean. ‡After diagnosis of anastomotic leakage (AL). ESC, early surgical closure; n, number of patients; EVT, endoscopic vacuum therapy.