Table 4.
The SEAL score after internal validation
| Predictor | Odds ratio |
|---|---|
| POD of diagnosis* | 1.43 (0.89, 2.29) |
| Level of care at diagnosis | |
| Surgical ward | 1.00 (reference) |
| ICU, MC, HC, PACU | 1.83 (1.19, 2.82) |
| Other | 1.31 (0.52, 3.29) |
| Diet at diagnosis | |
| Unrestricted | 1.00 (reference) |
| Liquids | 0.87 (0.46, 1.65) |
| Water | 0.45 (0.17, 1.21) |
| Nil by mouth | 1.02 (0.54, 1.90) |
| qSOFA score (per point) | 1.21 (0.88, 1.66) |
| Respiratory failure | 1.53 (0.90, 2.60) |
| Haemodynamic failure | 1.14 (0.62, 2.13) |
| Renal failure | 2.48 (1.30, 4.73) |
| Leucocyte count* | 0.92 (0.70, 1.20) |
| Resection type | |
| TTO-CA | 1.00 (reference) |
| TTO-IA | 0.69 (0.46, 1.04) |
| THO-CA | 0.68 (0.37, 1.26) |
| Defect circumference ≥25% | 1.66 (1.08, 2.57) |
| Overall conduit ischaemia/necrosis | 1.20 (0.73, 1.98) |
| Intrathoracic collections | |
| None | 1.00 (reference) |
| Drained | 1.48 (0.78, 2.82) |
| Undrained | 1.52 (0.98, 2.37) |
Values in parentheses are 95 per cent confidence intervals. *Interquartile OR, i.q.r.: postoperative day (POD) of diagnosis 5–11 days, leucocyte count 9.3–16.1 × 109/l. SEAL, Severity of oEsophageal Anastomotic Leak; ICU, intensive care unit; MC, medium care; HC, high care; PACU, postanaesthesia care unit; qSOFA, quick Sequential Organ Failure Assessment; TTO, transthoracic oesophagectomy; CA, cervical anastomosis; IA, intrathoracic anastomosis; THO, transhiatal oesophagectomy.