Table 2.
Main outcomes by surgical strategy for pancreatic fistula
| Outcomes | Completion pancreatectomy (n = 36) | Pancreas-preserving procedure (n = 126) | P |
|---|---|---|---|
| Death | 20 (56) | 40 (31.7) | 0.009 |
| Organ failure 24 h after initial relaparotomy † | 0.165 | ||
| No | 6 (17) | 34 (27.4) | |
| Single | 5 (14) | 26 (21.0) | |
| Multiple | 25 (69) | 64 (51.6) | |
| Highest APACHE II score 24 h after initial relaparotomy * † | 18 (15, 23) | 15 (11, 18) | <0.001 |
| ICU admission | 35 (97) | 107 (84.9) | 0.048 |
| Duration of ICU admission (days)* | 13 (3, 32) | 7 (2, 17) | 0.091 |
| Additional reintervention after initial relaparotomy | 23 (64) | 84 (66.7) | 0.756 |
| Radiological intervention | 16 (44) | 71 (56.3) | 0.206 |
| Relaparotomy | 14 (39) | 40 (31.7) | 0.423 |
| Secondary completion pancreatectomy | – | 10 (7.9) | |
| Additional reintervention for PPH after initial relaparotomy | 6 (17) | 21 (16.7) | >0.999 |
| Radiological intervention for PPH | 2 (6) | 12 (9.5) | 0.455 |
| Relaparotomy for PPH | 4 (11) | 10 (7.9) | 0.550 |
| Duration of hospital stay (days)* | 38 (24, 61) | 53 (31, 66) | 0.042 |
| Duration of hospital stay in survivors (days)* | 55 (31, 70) | 56 (40, 71) | 0.592 |
| New-onset postoperative pancreatic exocrine insufficiency in survivors † | – | 32 (43.2) | – |
| New-onset postoperative diabetes mellitus in survivors † | – | 19 (25.7) | – |
Continuous variables all compared using the Mann, Whitney U test. Categorical variables all compared using χ2. Except: additional reintervention for postpancreatectomy haemorrhage (PPH) after initial relaparotomy, radiological intervention for PPH, additional reintervention for PPH after initial relaparotomy, relaparotomy for PPH, which were compared with Fisher’s exact tests. Values in parentheses are percentages unless indicated otherwise
*values are median (i.q.r.).
†Missing data: organ failure 24 h after (n = 2), highest APACHE II score 24 h after (n = 28), new-onset postoperative pancreatic exocrine insufficiency (n = 14), new-onset postoperative diabetes mellitus (n = 14), APACHE, Acute Physiology And Chronic Health Evaluation; ICU, intensive care unit.