Table 6.
Risk factors for recurrent laryngeal nerve palsy identified by univariable and multivariable regression analyses
| RLN palsy† |
Univariable analysis |
Multivariable analysis |
||||
|---|---|---|---|---|---|---|
| Yes (n = 57) | No (n = 388) | Crude odds ratio* | P | Adjusted odds ratio* | P | |
| Lymph node dissection | ||||||
| None/excision | 3 (5) | 63 (16·2) | 1·00 (reference) | 1·00 (reference) | ||
| CLND | 20 (35) | 186 (47·9) | 2·26 (0·65, 7·86) | 0·200 | 2·82 (0·76, 10·39) | 0·120 |
| CLND + LLND | 34 (60) | 139 (35·8) | 5·14 (1·52, 17·36) | 0·008 | 4·04 (1·12, 14·58) | 0·033 |
| T category | ||||||
| p1 | 25 (44) | 277 (71·4) | 1·00 (reference) | 1·00 (reference) | ||
| p2 | 9 (16) | 59 (15·2) | 1·59 (0·68, 3·71) | 0·287 | 1·34 (0·55, 3·25) | 0·520 |
| p3 | 9 (16) | 41 (10·6) | 2·48 (1·08, 5·71) | 0·033 | 2·12 (0·88, 5·11) | 0·095 |
| p4 | 14 (26) | 11 (2·8) | 14·14 (5·49, 36·39) | < 0·001 | 12·16 (4·46, 33·18) | < 0·001 |
| Intraoperative nerve monitoring | ||||||
| No | 5 (9) | 31 (8·0) | 1·00 (reference) | 1·00 (reference) | ||
| Yes | 52 (91) | 357 (92·0) | 0·99 (0·32, 3·05) | 0·983 | 1·12 (0·32, 3·96) | 0·857 |
Values in parentheses are percentages, except
*
95 per cent confidence intervals.
†
Data after multiple imputation. There were missing data for T category (5·4 per cent) and intraoperative nerve monitoring (7·9 per cent). Seven patients with recurrent laryngeal nerve (RLN) palsy diagnosed on preoperative laryngoscopy were excluded. Multivariable analysis included all variables listed in the table. CLND, central lymph node dissection; LLND, lateral lymph node dissection.