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. 2023 May 19;37(4):1390–1400. doi: 10.1111/jvim.16727

FIGURE 5.

FIGURE 5

Scatter dot plots demonstrating platelet dependent thrombin generation over time in 9 cats, measured as (A) time (seconds) to maximum thrombin generation (T max), (B) peak thrombin generation (Relative Fluorescence Unit [RFU]), (C) thrombin generation potential (Area Under the Curve [AUC]) over 1 hour and (D) maximum velocity (V max, unit/s). After 7 days of treatment with rivaroxaban (RIVA), T max and peak thrombin generation were significantly modulated from D0 to D7. In addition to T max and peak thrombin generation, dual agent treatment (DAT) modulated thrombin generation potential and maximum velocity of thrombin generation from D0 to D7. Compared to RIVA, DAT also significantly prolonged T max compared to clopidogrel (CLOP) alone on D7. *P < .05; **P < .005; ***P < .001.