TABLE 1.
Blood gases and acid‐base measurements (mean ± SD) in dogs with induced acid‐base disturbances (n = 8)
| Variables | Acid‐base status | AB | ACV | ASV | |
|---|---|---|---|---|---|
| pH (unit) | Normal 1 a | 7.374 ± 0.044 | 7.352 ± 0.036 | 7.350 ± 0.046 | |
| Met. acidosis | 7.213 ± 0.070 | 7.186 ± 0.058 | 7.203 ± 0.064 | ||
| Met. alkalosis | 7.481 ± 0.043 | 7.460 ± 0.043 | 7.460 ± 0.047 | ||
| Normal 2 a | 7.392 ± 0.019 | 7.366 ± 0.017* | 7.368 ± 0.024 | ||
| Res. acidosis | 7.203 ± 0.053 | 7.180 ± 0.054 | 7.187 ± 0.053 | ||
| Res. alkalosis | 7.488 ± 0.029 | 7.468 ± 0.034 | 7.468 ± 0.030 | ||
| PCO2 (mm Hg) | Normal 1 a | 37.7 ± 3.1 | 40.2 ± 2.8 | 40.4 ± 3.3 | |
| Met. acidosis | 33.2 ± 3.0 | 38.7 ± 2.6** | 37.5 ± 2.6* | ||
| Met. alkalosis | 43.6 ± 3.8 | 47.6 ± 4.9 | 46.8 ± 4.3 | ||
| Normal 2 a | 37.7 ± 2.4 | 41.3 ± 3.0* | 40.9 ± 2.2 | ||
| Res. acidosis | 62.3 ± 9.4 | 68.0 ± 10.0 | 65.6 ± 9.8 | ||
| Res. alkalosis | 25.4 ± 3.5 | 28.3 ± 3.1 | 28.6 ± 3.9 | ||
| PO2 (mm Hg) | Normal 1 a | FIO2 0.21, n = 8 | 80.6 ± 7.6 | 55.0 ± 4.5** | 56.7 ± 7.1** |
| Met. acidosis | FIO2 0.21, n = 7 | 95.0 ± 16.3 | 53.5 ± 6.8** | 59.2 ± 6.2** | |
| FIO2 1.0, n = 1 | 528.4 | 79.0 | 249.0 | ||
| Met. alkalosis | FIO2 0.21, n = 7 | 83.7 ± 5.3 | 52.5 ± 5.3** | 52.9 ± 6.1** | |
| FIO2 1.0, n = 1 | 571.5 | 55.6 | 57.4 | ||
| Normal 2 a | FIO2 0.21, n = 8 | 77.1 ± 10.4 | 52.4 ± 10.9** | 54.4 ± 10.7** | |
| Res. acidosis | FIO2 0.21, n = 0 | ND | ND | ND | |
| FIO2 1.0, n = 8 | 554.0 ± 20.6 | 154.8 ± 95.8** | 235.5 ± 140.0** | ||
| Res. alkalosis | FIO2 0.21, n = 8 | 87.3 ± 11.6 | 48.6 ± 8.8** | 51.6 ± 6.7** | |
| FIO2 1.0, n = 0 | ND | ND | ND | ||
| [HCO3 −] (mmol/L) | Normal 1 a | 21.5 ± 1.5 | 21.8 ± 1.5 | 21.8 ± 1.7 | |
| Met. acidosis | 13.2 ± 2.5 | 14.5 ± 2.5 | 14.5 ± 2.4 | ||
| Met. alkalosis | 31.9 ± 4.1 | 33.3 ± 5.0 | 32.7 ± 4.6 | ||
| Normal 2 a | 22.4 ± 1.3 | 23.1 ± 1.3 | 23.0 ± 1.3 | ||
| Res. acidosis | 24.0 ± 3.8 | 24.8 ± 4.1 | 24.3 ± 3.7 | ||
| Res. alkalosis | 18.8 ± 2.1 | 19.9 ± 1.3 | 20.2 ± 1.8 | ||
| BE (mmol/L) | Normal 1 a | −3.1 ± 2.0 | −3.4 ± 1.8 | −3.4 ± 2.2 | |
| Met. acidosis | −13.3 ± 3.5 | −12.8 ± 3.1 | −12.6 ± 3.3 | ||
| Met. alkalosis | 7.5 ± 3.9 | 7.9 ± 4.5 | 7.6 ± 4.3 | ||
| Normal 2 a | −2.0 ± 1.2 | −2.0 ± 1.0 | −2.0 ± 1.4 | ||
| Res. acidosis | −5.1 ± 3.4 | −5.0 ± 3.7 | −5.3 ± 3.4 | ||
| Res. alkalosis | −2.6 ± 1.8 | −2.1 ± 1.6 | −2.0 ± 1.3 |
Abbreviations: AB, arterial blood; ACV, arterialized cephalic venous blood; ASV, arterialized saphenous venous blood; Met., metabolic; Res., respiratory.
a
Refer to Figure 1.
*
Significantly different (p < .05) from AB.
**
Significantly different (p < .01) from AB.