TABLE 3.

The gene identification, protein, name log₂ fold change (FC) and adjusted P value for significantly differentially expressed upregulated proteins in the lateral cerebellar hemispheres of Shivers vs control horses.

Gene ID	Proteins	Log2 FC	AdjP value
Cytoskeleton
VCL	Vinculin isoform X1	0.26	<.0001
VIM	Cluster of vimentin	0.36	<.0001
DES	Desmin	0.29	<.0001
PFN1	Profilin‐1	0.21	.001
FLNA	Cluster of filamin‐A isoform X1	0.29	<.0001
CALD1	Caldesmon isoform X2	0.26	.002
TAGLN	Transgelin	0.3	<.0001
Extracellular matrix
COL6A2	Collagen alpha‐2(VI) chain isoform X1	0.12	.002
COL6A3	Collagen alpha‐3(VI) chain isoform X3	0.27	<.0001
OGN	Mimecan isoform X1	0.23	<.0001
DCN	Decorin precursor	0.23	.0005
BGN	Biglycan precursor	0.33	.0001
PRELP	Prolargin	0.3	<.0001
TLN1	Talin‐1 isoform X3	0.22	.0001
Redox balance
PGD	6‐phosphogluconate dehydrogenase, decarboxylating	0.09	.001
TXNDC17	Thioredoxin domain‐containing protein 17	0.18	.002
Neurite outgrowth
AHNAK	Neuroblast differentiation‐associated protein AHNAK isoform X1	0.21	.0004
Signal transduction
ANXA2	Annexin A2	0.32	<.0001
Lipid metabolism
APOB	Apolipoprotein A‐I	0.2	<.0001
Protein synthesis
EET2	Elongation factor 2	0.09	.0005
Blood‐borne
HBB	Cluster of hemoglobin subunit beta	0.36	.002
ALB	Serum albumin precursor	0.23	<.0001
A2M	Alpha‐2‐macroglobulin	0.22	<.0001