FIGURE 3.
Protein‐protein interaction network for differentially expressed proteins between cats with chronic enteropathies and controls shows 2 distinct clusters (red and green) representing the involvement of the (a) extracellular matrix (ECM) and (b) altered coagulation, lipid regulation in the inflammatory state. ACTB, actin; APOA1, apolipoprotein A1; APOB, apolipoprotein B; APOC3, apolipoprotein C3; APOE, apolipoprotein E; CLU, clusterin; CPAMD8, C3 and PZP‐like alpha‐2‐macroglobulin domain containing protein 8; F5, coagulation factor V; F9, coagulation factor IX; FGB, fibrinogen beta chain; FN1, fibronectin; GSN, gelsolin; HBB, hemoglobin subunit beta; HPX, hemopexin; ITIH2, inter alpha trypsin inhibitor heavy chain H2; ITIH3, inter alpha trypsin inhibitor heavy chain H3; LCAT, phosphatidylcholine‐sterol acyltransferase; LCP1, plastin 2; PFN1, profilin 1; PON1, serum paraoxonase/arylesterase 1; SERPINC1, antithrombin‐III; SERPIND1, heparin cofactor 2; SERPINF2, alpha‐2‐antiplasmin; TAGLN2, transgelin‐2; THBS1, thrombospondin 1; TPM4, tropomyosin alpha‐4 chain; TTR, transthyretin; VCL, vinculin.