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. 2022 Mar 10;2:837191. doi: 10.3389/fradi.2022.837191

Table 3.

Koos classification results obtained from automatic methods and human annotators using 5-fold cross-validation.

MA-MAE F1 score (%) Accuracy (%)
ceT1
Baseline 0.23 ± 0.11 76.1 ± 6.3 76.6 ± 5.6
DenseNet 0.17 ± 0.04 81.5 ± 5.1 81.5 ± 5.1
Random forest 0.12 ± 0.05 87.6 ± 3.0 87.6 ± 3.0
hrT2
Baseline 0.22 ± 0.05 79.4 ± 2.1 79.5 ± 2.0
DenseNet 0.15 ± 0.06 83.8 ± 5.8 83.8 ± 5.8
Random forest 0.14 ± 0.06 85.2 ± 4.8 85.2 ± 4.8
ceT1 + hrT2
Baseline 0.22 ± 0.05 77.1 ± 3.7 77.2 ± 3.8
DenseNet 0.18 ± 0.05 82.1 ± 5.0 82.1 ± 5.0
Random forest 0.12 ± 0.06 87.2 ± 2.8 87.2 ± 2.8
Ensemble
DenseNet + 0.11 ±0.05 89.3 ±3.0 89.3 ±2.9
Random forest
Human annotators
Annotator 1 0.17 ± 0.07 85.4 ± 4.0 84.4 ± 4.7
Annotator 2 0.06 ± 0.02 92.9 ± 3.2 92.9 ± 3.1
Average human annotator 0.11 ± 0.08 89.1 ± 5.2 88.6 ± 5.8

The columns correspond to the weighted macro-averaged mean absolute error (MA-MAE), the weighted macro-averaged F1 score, and the accuracy score. Inputs are contrast-enhanced T1-weighted (ceT1) images, high-resolution T2-weighted (hrT2) images, or a combination of both (ceT1 + hrT2). The error ranges correspond to the standard deviation of the mean of values obtained from 5-fold cross-validation. Bold scores indicate the best automatic method.