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. Author manuscript; available in PMC: 2023 Jul 24.
Published in final edited form as: Org Biomol Chem. 2022 Mar 9;20(10):2075–2080. doi: 10.1039/d1ob02127c

Fig. 2.

Fig. 2

Design and EKO evaluation of target compounds. (a) The peptide backbone is replaced with two 5-membered aromatic rings. (b) The structure and retrosynthesis of TT-mer. (c) A simulated conformer of TT-mer overlays on the interface triplet found on bovine pancreatic trypsin inhibitor (BPTI) with an RMSD of 0.37 Å.