Table 3.

Brain regions showed significant differences in RTdose images between RTtechs (IMRT vs. VMAT) in all patients in a two-sample t-test by using a permutation threshold-free cluster enhancement test (number of permutations = 5,000, FWE p < 0.05), voxel size: 2*2*2.

Regions	Voxels	Peak T value	MNI coordinate
			x	y	z
IMRT < VMAT
Cerebellum Posterior Lobe	9,153	−11.72	26	−86	−48
Frontal Lobe	4,264	−5.31	14	38	2
Occipital Lobe	4,222	−7.06	24	−94	−26
Sub-lobar	3,859	−5.79	−2	−50	−44
Cerebellum Anterior Lobe	2,067	−6.81	−18	−66	−34
Limbic Lobe	1,210	−5.27	10	38	2
Temporal Lobe	993	−5.68	−58	−54	−24
Medulla	337	−8.06	2	−48	−52
Pons	297	−5.29	0	−44	−42
IMRT > VMAT
Temporal Lobe	4,592	8.30	−22	10	−26
Frontal Lobe	3,212	9.27	−12	12	−26
Limbic Lobe	1,771	9.12	14	2	−24
Midbrain	1,061	8.07	−4	−10	−22
Pons	317	8.14	6	−10	−24
Sub-lobar	203	5.24	26	−6	−24