Table 6.

Brain regions showed significant differences in RTdose images between RTtechs (IMRT vs. VMAT) in T4 patients in a two-sample t-test by using a permutation threshold-free cluster enhancement test (number of permutations = 5,000, FWE p < 0.05), voxel size: 2*2*2.

Regions	Voxels	Peak T value	MNI coordinate
			x	y	z
IMRT < VMAT
Cerebellum Posterior Lobe	7,381	−7.21	−24	−88	−46
Occipital Lobe	2,594	−5.39	−26	−92	−26
Frontal Lobe	2,399	−3.83	30	62	−16
Cerebellum Anterior Lobe	1,969	−5.88	−48	−44	−30
Temporal Lobe	1,940	−6.64	−58	−54	−24
Pons	1,060	−6.13	2	−32	−40
Limbic Lobe	981	−4.27	−38	−16	−36
Sub-lobar	719	−4.96	−2	−50	−44
Medulla	452	−6.41	0	−46	−52
IMRT > VMAT
None