Table 3.

Orbitofrontal Cortex Resting-state Connectivity Suppressed and Mediated the Negative Relationship between Uncinate Fasciculus Volume and Infant Negative Emotionality

Resting-state Connectivity Seed: Orbitofrontal Cortex (OFC) – Limbic, DMN
Coordinates	Regions	k	a	b	Direct	Total	Indirect	Indirect CIs	M/S
Amygdala left	−18, −5, −10	12	−4.53E-04	−3.29E-01	−3.91E-04	−2.42E-04	1.49E-04	0.000042, 0.000418	S
Inferior frontal gyrus triangular left	−30, 18, 7	86	−4.69E-04	−2.64E-01	−3.65E-04	−2.42E-04	1.24E-04	0.000050, 0.000388	S
Middle temporal gyrus left	−34, −28, 0	60	−4.58E-04	−2.03E-01	−3.35E-04	−2.42E-04	9.30E-05	0.000022, 0.000323	S
Orbitofrontal cortex inferior left	−25, 21, −2	13	−4.63E-04	−8.02E-02	−2.79E-04	−2.42E-04	3.71E-05	0.000001, 0.000291	S
Superior frontal gyrus dorsal left	−10, 20, 30	39	4.36E-04	−1.43E-01	−1.79E-04	−2.42E-04	−6.26E-05	−0.000321, −0.000009	M
Superior frontal gyrus medial right	5, 25, 25	10	3.57E-04	−1.55E-01	−1.86E-04	−2.42E-04	−5.52E-05	−0.000432, −0.000006	M
Supramarginal gyrus left	−34, −30, 22	18	2.65E-04	−1.80E-01	−1.94E-04	−2.42E-04	−4.76E-05	−0.000221, 0.000019	M
Superior temporal gyrus left	−30, −27, 14	15	1.91E-04	−2.01E-01	−2.03E-04	−2.42E-04	−3.85E-05	−0.000185, 0.000021	M
Middle frontal gyrus left	−19, 12, 31	32	3.39E-04	−1.00E-01	−2.08E-04	−2.42E-04	−3.39E−05	−0.000279, 0.000001	M
Angular gyrus left	−33, −37, 23	31	2.40E-04	−1.34E-01	−2.09E-04	−2.42E-04	−3.22E-05	−0.000320, 0.000001	M
Inferior parietal lobule left	−35, −30, 29	18	1.95E-04	−1.35E-01	−2.15E-04	−2.42E-04	−2.64E-05	−0.000248, 0.000006	M
Superior frontal gyrus medial left	−2, 25, 26	26	8.80E-05	−2.09E-02	−2.40E-04	−2.42E-04	−1.84E-06	−0.000405, 0.000013	M

k – number of voxels within a cluster; a – independent variable-to-mediator relationship; b - mediator-to-dependent variable relationship; M/S – Mediation/Suppression.