Table 4.

Demographic characteristics of individuals with confirmed sickle cell disease (SCD), likely SCD, those not having SCD, and those with an indeterminate status identified by the clinical validation process by state over a 3-year period.

		Alabamaa (n=328)					Georgiab (n=684)					Wisconsinc (n=420)
		Confirmed SCD (n=302)	Likely SCD (n=8)	Confirmed as not having SCD (n=12)	Indeterminant status (n=6)	Confirmed SCD (n=638)		Likely SCD (n=0)	Confirmed as not having SCD (n=21)	Indeterminant status (n=25)	Confirmed SCD (n=340)		Likely SCD (n=4)	Confirmed as not having SCD (n=28)	Indeterminant status (n=48)
Age (years), mean (SD)		28.0 (9.5)	32.9 (5.1)	28.58 (6.3)	36.8 (12.2)	29.6 (10.5)		N/Ad	31.1 (9.6)	39.2 (14.5)	36.7(10.5)		43.8 (11.5)	37.4(8.6)	46.4 (14.9)
Age groups (years), n (%)
	18-29	210 (70)	1 (12)	8 (67)	3 (50)	380 (60)		N/A	10 (48)	7 (28)	101 (30)		0 (0)	5 (18)	7 (14)
	30-39	55 (18)	7 (88)	4 (33)	2 (33)	160 (25)		N/A	6 (29)	9 (36)	129 (38)		1 (25)	12 (43)	9 (19)
	40-49	23 (8)	—e	—	1 (17)	63 (10)		N/A	5 (24)	2 (8)	64 (19)		2 (50)	9 (32)	15 (31)
	50-59	11 (4)	—	—	1 (17)	23 (4)		N/A	—	4 (16)	37 (11)		1 (25)	2 (7)	8 (17)
	≥60	3 (1)	—	—	—	12 (2)		N/A	—	3 (12)	9 (3)		0 (0)	0 (0)	9 (19)
Sex (female), n (%)		192 (64)	7 (88)	7 (58)	3 (50)	358 (56)		N/A	19 (90)	19 (76)	183 (54)		3 (75)	21 (75)	35 (73)
SCD encounters per patient during the study period, mean (SD)		32.4 (20.2)	22 (17)	15.1 (7.1)	16.2 (13.5)	53.9 (62.7)		N/A	12.6 (14.9)	11.7 (26.3)	40.3 (43.7)		7.5 (2.6)	11.3 (20.7)	26.5 (72.0)

^aSCD types in Alabama: hemoglobin SS/Sβ0, n=199 (66%); hemoglobin SC, n=57 (19%); others, n=46 (15%).

^bSCD types in Georgia: hemoglobin SS/Sβ0, n=458 (72%); hemoglobin SC, n=146 (23%); others, n=34 (5%).

^cSCD types in Wisconsin: hemoglobin SS/Sβ0, n=220 (65%); hemoglobin SC, n=86 (25%); others, n=35 (10%).

^dN/A: not applicable.

^eNot available.