. 2023 Jun 27;9:e45848. doi: 10.2196/45848

Table 2.

Top 10 conditions in terms of the observed/expected ratio and exclusivity for the heart & circulatory and mental & neurodegenerative patterns.

Pattern and disease			Multimorbidity & frailty					Multimorbidity & age
			OE^a ratio		Exclusivity, %		OE ratio			Exclusivity, %
Heart & circulatory
	Heart failure	7.86^b		54.38^b		7.67^b			55.57^b
	Cardiac valve diseases	7.37^b		50.98^b		7.24^b			52.47^b
	Atrial fibrillation	6.54^b		45.29^b		6.46^b			46.81^b
	Bradycardia and conduction diseases	5.75^b		39.83^b		5.87^b			42.57^b
	Ischemic heart disease	3.69^b		25.51^b		3.62^b			26.22^b
	Chronic kidney diseases	2.30^b		15.95		2.23^b			16.17
	Anemia	2.29^b		15.85		2.21^b			16.05
	Cerebrovascular disease	2.16^b		14.93		2.13^b			15.41
	COPD^c, emphysema, and chronic bronchitis	2.07^b		14.33		1.99			14.43
	Inflammatory arthropaties	1.86		12.85		N/A^d			N/A
	Chronic pancreas diseases, and biliary tract and gallbladder diseases	N/A		N/A		1.75			12.67
Mental & neurodegenerative
	Parkinson disease and parkisonism	19.98^b		90.67^b		9.24^b			73.46^b
	Other neurological diseases	18.54^b		84.14^b		4.68^b			37.19^b
	Dementia	2.24^b		10.18		6.95^b			55.24^b
	Cerebrovascular disease	2.10^b		9.53		3.39^b			26.92^b
	Depression and mood diseases	1.76		8.00		2.20^b			17.50^b
	Colitis and related diseases	1.48		6.71		1.83			14.59
	Anemia	1.38		6.28		2.17^b			17.26
	Sleep disorders	1.37		6.22		N/A			N/A
	Other digestive diseases	1.35		6.11		4.57^b			36.36^b
	Dorsopathies	1.33		6.05		N/A			N/A
	Chronic kidney diseases	N/A		N/A		1.65			13.10
	Deafness and hearing impairment	N/A		N/A		1.47			11.69

^aOE: observed/expected.

^bThe conditions used to name the pattern. The conditions for the rest of the patterns can be found in Multimedia Appendix 4.

^cCOPD: chronic obstructive pulmonary disease.

^dN/A: not applicable.