Table 4.
Data for the unadjusted survival models using the multimorbidity patterns as the time-varying covariate.
| Patterna,b | Mortality | Nursing home admission | Home care need | |||||
|
|
Multimorbidity & age, HRc (95% CI) | Multimorbidity & frailty, HR (95% CI) | Multimorbidity & age, HR (95% CI) | Multimorbidity & frailty, HR (95% CI) | Multimorbidity & age, HR (95% CI) | Multimorbidity & frailty, HR (95% CI) | ||
| Allergy & migraine | 0.39 (0.39-0.70) | 0.43 (0.42-0.44) | 1.68 (1.61-1.76) | 1.53 (1.45-1.61) | 2.50 (2.41-2.59) | 2.98 (2.87-3.10) | ||
| Autoimmune & metabolic | 0.97 (0.96-0.99) | N/Ad | 2.51 (2.40-2.62) | N/A | 4.66 (4.52-4.81) | N/A | ||
| Chronic ulcers & peripheral vascular | 6.94 (6.85-7.03) | 6.87 (6.78-6.96) | 22.28 (21.47-23.12) | 23.43 (22.58-24.31) | 26.25 (25.44-27.08) | 34.36 (33.24-35.52) | ||
| Dementia & motility digestive | N/A | 2.88 (2.86-2.92) | N/A | 22.95 (22.25-23.67) | N/A | 25.38 (24.67-26.12) | ||
| Diabetes & obesity | 0.7 (0.69-0.71) | 0.62 (0.61-0.63) | 1.62 (1.56-1.69) | 1.42 (1.37-1.48) | 0.68 (0.67-0.69) | 3.23 (3.13-3.34) | ||
| Genitourinary & respiratory | 0.8 (0.79-0.81) | 1.05 (1.04-1.07) | 1.22 (1.16-1.28) | 1.48 (1.42-1.55) | 1.69 (1.63-1.75) | 2.97 (2.86-3.07) | ||
| Heart & circulatory | 3.14 (3.10-3.18) | 3.07 (3.03-3.10) | 7.71 (7.45-7.98) | 8.13 (7.86-8.42) | 15.64 (15.23-16.07) | 21.59 (20.97-22.22) | ||
| Mental & neurodegenerative | 3.56 (3.52-3.60) | 1.96 (1.93-1.99) | 24.41 (23.66-25.18) | 10.91 (10.53-11.30) | 20.46 (19.93-21.00) | 16.98 (16.46-17.51) | ||
| Neuromusculoskeletal | 0.32 (0.31-0.33) | 0.31 (0.31-0.32) | 1.61 (1.54-1.68) | 1.43 (1.36-1.49) | 3.36 (3.25-3.46) | 3.83 (3.70-3.96) | ||
| Peripheral vascular & respiratory | 2.04 (2.01-2.07) | 1.98 (1.95-2.01) | 3.99 (3.82-4.17) | 4.02 (3.85-4.20) | 7.53 (7.30-7.77) | 9.54 (9.23-9.87) | ||
| Respiratory | 0.9 (0.89-0.92) | 0.87 (0.86-0.89) | 3.11 (2.98-3.26) | 2.98 (2.84-3.12) | 5.78 (5.60-5.97) | 7.10 (6.86-7.35) | ||
| AICe | 9,605,078f | 9,637,872 | 10,261,814 | 9,996,581f | 10,945,802 | 10,924,083f | ||
| R2 | 0.37f | 0.32 | 0.21 | 0.38f | 0.36 | 0.39f | ||
| AUCg | 0.713f | 0.705 | 0.718f | 0.717 | 0.719 | 0.721f | ||
aNonspecific was used as reference.
bAll P<.001.
cHR: hazard ratio.
dN/A: not applicable.
eAIC: Akaike Information Criterion.
fThe set of patterns that achieved better performance for each metric and outcome.
gAUC: area under the receiver operating characteristic curve.