Fig. 2.
LSG-induced increases in SC of the Hb-Hy. Increases in SC of Hb-Hy were correlated with reductions in HAMD and DEBQ-external eating at PostLSG12. TFEQ-hunger was negatively correlated with SC of Hb-Hy at PostLSG12. Only the correlation slope between SC of Hb-Hy and TFEQ-hunger was significantly different. The error bars indicate standard error of the mean. Abbreviation: Hb, habenula; Hy, hypothalamus; FA, fractional anisotropy; SC, structural connectivity; HAMD, Hamilton depression; TFEQ, three factor eating questionnaire; DEBQ, Dutch Eating Behavior Questionnaire; LSG, laparoscopic sleeve gastrectomy; PreLSG, participants with obesity who received MRI scan before surgery; PostLSG12, participants with obesity who received MRI scan at 12 months after surgery; NW, normal weight.