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Summary of enzymes with the enhanced stereoselectivity through the date-driven enzyme engineeringa
| Enzyme | Substrate | Mutation | Performance | Paper |
|---|---|---|---|---|
| Epoxide hydrolase | Glycidyl phenyl ether | L215F/A217N/L249Y/T317W/T318V/M329P/C350V | E-value = 253 | 2018-Cadet (Cadet et al., 2018) |
| Nitric oxide dioxygenase | Phenyldimethyl silane, ethyl 2-diazopropanoate | R51V | % ee = 93 | 2019-Wu (Wu et al., 2019) |
aIn the column of Mutation and Performance, only the best-performing enzyme mutants are shown.
