Table 3. Overview of hemostatic parameters and the corresponding clinical tests.
Hemostatic factor/process | Corresponding test |
---|---|
Platelet adhesion | Platelet function analyzer (PFA) |
Platelet secretion | Lumiaggregometry (ATP release) Flow cytometry (P-selectin) |
Platelet aggregation | Aggregometry (e.g., light transmission aggregometry, multiple electrode impedance aggregometry) Platelet function analyzer (PFA) Flow cytometry |
Coagulation | PT, aPTT, thrombin generation Viscoelastic methods (e.g., ROTEM, TEG) Coagulation factor determination |
vWF | Platelet function analyzer (PFA) Platelet agglutination assay vWF antigen and activity assay |
Hematocrit | Hematology analyzer |
Shear-dependent platelet function | Platelet function analyzer (PFA) |
Vasoconstriction | No test available, bleeding time is obsolete |
Abbreviation: aPTT, activated partial thromboplastin time; PT, prothrombin time; ROTEM, rotational thromboelastography; TEG, thromboelastography; vWF, von Willebrand factor.