Table 2.
Retention time, multiple reaction monitoring transitions, dwell time, cone voltage, collision energy for analytes, and internal standards.
| Compound name | Retention time (min) | Precursor ion (m/z) | Product ion (m/z) | Dwell time (ms) | Cone voltage (V) | Collision energy (V) | Internal standard |
|---|---|---|---|---|---|---|---|
| Mephedrone | 5.38 | 178.00 | 160.00 | 0.003 | 18 | 12 | Mephedrone-D3 |
| 145.00 | 18 | 22 | |||||
|
| |||||||
| Butylone | 5.54 | 222.10 | 174.10 | 0.003 | 25 | 15 | Butylone-D3 |
| 204.10 | 30 | 10 | |||||
| Pentylone | 6.47 | 236.00 | 188.00 | 0.008 | 24 | 20 | Butylone-D3 |
| 218.00 | 24 | 12 | |||||
|
| |||||||
| Eutylone | 6.01 | 236.00 | 188.00 | 0.008 | 36 | 25 | Butylone-D3 |
| 218.00 | 36 | 19 | |||||
|
| |||||||
| Ephylone | 6.89 | 250.00 | 202.00 | 0.008 | 31 | 26 | Butylone-D3 |
| 174.00 | 31 | 41 | |||||
|
| |||||||
| 4-MEAPP | 7.43 | 220.00 | 105.00 | 0.022 | 12 | 26 | Butylone-D3 |
| 144.00 | 12 | 38 | |||||
|
| |||||||
| PMA | 4.60 | 166.00 | 149.00 | 0.003 | 25 | 8 | MDA-D5 |
| 121.00 | 25 | 20 | |||||
|
| |||||||
| PMMA | 5.15 | 180.10 | 120.91 | 0.003 | 30 | 22 | MDA-D5 |
| 91.10 | 30 | 30 | |||||
|
| |||||||
| DCK | 6.04 | 204.00 | 173.00 | 0.008 | 21 | 17 | Ketamine-D4 |
| 145.00 | 21 | 24 | |||||
|
| |||||||
| 2-FDCK | 5.88 | 222.00 | 109.00 | 0.008 | 22 | 25 | Ketamine-D4 |
| 163.00 | 22 | 25 | |||||
|
| |||||||
| Mephedrone-D3 | 5.37 | 180.79 | 147.89 | 0.003 | 40 | 18 | — |
| 144.83 | 38 | 20 | |||||
|
| |||||||
| Butylone-D3 | 5.53 | 225.03 | 177.07 | 0.003 | 36 | 18 | — |
| 148.94 | 36 | 26 | |||||
|
| |||||||
| MDA-D5 | 4.47 | 185.00 | 168.00 | 0.003 | 20 | 10 | — |
| 110.00 | 20 | 20 | |||||
|
| |||||||
| Ketamine-D4 | 6.59 | 242.00 | 129.00 | 0.008 | 20 | 30 | — |
| 224.00 | 20 | 20 | |||||
LC-MS/MS: liquid chromatography-tandem mass spectrometry; mephedrone: 4-methylmethcathinone; ephylone: N-ethylpentylone; 4-MEAPP: 4-methyl-α-ethylaminopentiophenone; PMA: para-methoxyamphetamine; PMMA: para-methoxymethamphetamine; DCK: deschloroketamine; 2-FDCK: 2-fluorodeschloroketamine; MDA-D5: 3,4-methylenedioxyamphetamine-D5.