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. 2022 Oct 14;7(14):3612–3623. doi: 10.1182/bloodadvances.2022007715

Table 1.

Cellular and plasma cGVHD markers with a selection frequency greater than or equal to 0.99 in the diagnostic cGVHD classifier

Cell type or plasma protein Immune phenotype or plasma protein Selection frequency
NKreg noncytolytic CD56bright Perforin 0.999
NKreg noncytolytic CD56bright Granzyme B 0.999
Naïve Th cells CD4+ CD45RA+ PD1 1
Naïve Th cells CD4+ CD45RA+ CCR7+ 1
Naïve Th cells CD4+ CD45RA+ CD27+ 1
Naïve Th cells (RTE) CD4+ CD45RA+ CD31+ 1
Naïve Tc cells CD8+ CD45RA+ CCR7+ 0.994
Naïve Treg cells CD45RA+ PD1 Treg 1
Naïve Treg cells (RTE) CD45RA+ CD31+ Treg 1
Plasma protein CXCL9 1
Plasma protein CXCL10 (IP10) 0.998
Plasma protein CXCL11 1
Plasma protein ICAM-1 1
Plasma protein TIM-3 0.999
Plasma protein ST2 1

RTE, recent thymic emigrant.