Table 3.
Age, number of drugs, number of uterotonics, and the reported outcomes, stratified by the two drugs and the haemodynamic effects of interest
| Hypotension | Hypertension | Tachycardia | Bradycardia | |||||
|---|---|---|---|---|---|---|---|---|
| O | C | O | C | O | C | O | C | |
| Total (%)* | 223 (2.0) | 19 (5.1) | 80 (0.7) | 9 (2.4) | 231 (2.1) | 21 (5.6) | 91 (0.8) | 6 (1.6) |
| Outcome (%)† | ||||||||
| Death | 4 (1.8) | 0 | 1 (1.3) | 0 | 6 (2.6) | 0 | 2 (2.2) | 0 |
| Not recovered/recovered with a sequela | 2 (0.9) | 1 (5.3) | 5 (6.3) | 0 | 2 (0.9) | 1 (4.8) | 3 (3.3) | 0 |
| Recovering | 11 (4.9) | 2 (10.5) | 11 (13.8) | 2 (22.2) | 42 (18.2) | 3 (14.3) | 8 (8.8) | 0 |
| Fully recovered | 150 (67.3) | 14 (73.7) | 47 (58.8) | 7 (77.8) | 143 (61.9) | 11 (52.4) | 59 (64.8) | 5 (83.3) |
| Unknown | 31 (13.9) | 2 (10.5) | 11 (13.8) | 0 | 21 (9.1) | 1 (4.8) | 15 (16.5) | 0 |
| Not reported | 25 (11.2) | 0 | 5 (6.3) | 0 | 17 (7.4) | 5 (23.8) | 4 (4.4) | 1 (16.7) |
| Age [y], Mean (SD) | 30.0 (6.2) | 34.8 (14.8) | 30.0 (6.8) | 34.2 (5.8) | 29.5 (8.2) | 30.6 (3.6) | 29.9 (8.6) | 31.8 (3.3) |
| Other uterotonics present (%)† | 12 (5.4) | 2 (10.5) | 18 (22.5) | 2 (22.2) | 15 (6.5) | 2 (9.5) | 3 (3.3) | 0 |
| Adrenergics present (%)† | 12 (5.4) | 2 (10.5) | 5 (6.3) | 0 | 9 (3.9) | 2 (9.5) | 0 | 1 (16.7) |
O = Oxytocin; C = Carbetocin; Uterotonics included: “Methylergometrine”, “Ergot alkaloids”, “Ergometrine”, “Dinoprostone”, “Gemeprost”, “Carboprost”, “Sulprostone”, “Misoprostol”. Adrenergics included: “Etilefrine”, “Isoprenaline”, “Norepinephrine”, “Dopamine”, “Norfenefrine”, “Phenylephrine”, “Dobutamine”, “Oxedrine”, “Metaraminol”, “Methoxamine”, “Mephentermine”, “Dimetofrine”, “Prenalterol”, “Dopexamine”, ”Gepefrine”, “Ibopamine”, “Midodrine”, “Octopamine”, “Fenoldopam”, “Cafedrine”, “Arbutamine”, “Theodrenaline”, “Epinephrine”, “Amezinium Metilsulfate”, “Ephedrine”, “Droxidopa”
*The percentage refers to all reports of the respective drug
†The percentage refers to the respective outcome and the respective drug