Table 1.
Patient cases - demographics and information on structured medication reviews
| Remote phase | Ward-based phase | p value | |
|---|---|---|---|
| Intensive care patients (cases, n) | 133 | 130 | |
| Age (years);mean (± standard deviation) | 63 (± 17.1) | 63 (± 13.2) | p = 0.709a |
| Male | 64% (85/133) | 63% (82/130) | p = 0.888b |
| Female | 36% (48/133) | 37% (48/130) | |
| Interdisciplinary ward | 56% (75/133) | 60% (77/130) | p = 0.641b |
| Surgical ward | 44% (58/133) | 40% (53/130) | |
| Medication reviews per patient case; (median, IQR) | 2 (1.5–4) | 2 (1–4) | |
| 1 medication review per patient case | 25% (33/133) | 48% (63/130) | p < 0.001b |
| 2 medication reviews per patient case | 26% (35/133) | 18% (23/130) | |
| 3 medication reviews per patient case | 19% (25/133) | 8% (10/130) | |
| > 3 medication reviews per patient case | 30% (40/133) | 26% (34/130) | |
| Patients per remote consultation/MDT round; (median, IQR) | 20 (19–22)) | 20 (19–21.75) | p = 0.958a |
| Pharmacist intervention per patient case (median, IQR) | 1 (0–3) | 1 (0–3.25) | p = 0.713a |
| Medication reviews (n) | 574 | 449 | |
| Medication review with pharmacist intervention | 36% (208/574) | 42% (188/449) | p = 0,066b |
| Pharmacist intervention per medication review, mean (± standard deviation) | 0.53 (± 0.8) | 0.67 (± 0.9) | p = 0.021a |
| Valid medication lines per medication review, (median, IQR) | 18 (14–22) | 19 (15–23) | p = 0.215c |
| Pharmacist intervention per remote consultation/MDT rounds; (median, IQR) | 8 (6–14.25) | 10.5 (8–15) | p = 0.177a |
| Mechanical ventilation | 69% (396/574) | 61% (273/449) | p = 0.888b |
| SAPS-II/TISS-10 information available1 | 540/574 | 427/449 | |
| SAPS-II (median, IQR) | 41 (33–50) | 41 (31–49) | p = 0.401c |
| TISS-10 (median, IQR) | 14 (10–17) | 12 (8–17) | p < 0.001a |
| Renal function, information available (n) | 98.9% (568/574) | 99.8% (448/449) | |
| Renal replacement therapy (n) | 31% (177/568) | 45% (204/448) | p < 0.001b |
| GFR (mL/min/1.73m2, (median, IQR) | 64 (40–93) | 80.5 (48.25–103.75) | p < 0.001c |
SAPS-II, simplified acute physiology score II; TISS-10, therapeutic intervention scoring system; MDT, multi-disciplinary-teams; IQR, interquartile range; GFR, glomerular filtration rate
1SAPS-II and TISS-10 data was not available, if patients had been onward for less than 24 h and were discharged that day
aMann–Whitney-U-test; bChi-Square-test; ct-test
Bold font is used to distinguish between data for patient cases and data which refers to medication reviews