Table 3.

Material parameters and data required by the numerical simulations

Parameter	Symbol	Value	Units
Maximum amount of available ligands on $\partial \mathrm{\Omega }(t)$	$c_{{\text{L}}_R}^{\mathit{av}}$	90.00	$\left[\text{mol},·,\mu m^{-2}\right]$
Ligands saturation limit	$c_{\text{L}}^{\max }$	$16·{10}^3$	$\left[\text{mol},·,\mu {\text{m}}^{-2}\right]$
Equilibrium constant	$K_{\text{eq}}^{(7}$	354058.32	$\left[-\right]$
Receptor diffusivity	$\text{D}|{}_R$	0.198	$\left[\mu {\text{m}}^2,·,s^{-1}\right]$
Bulk modulus cytoplasm	$\kappa$	12.82	$\left[\text{Pa}\right]$
Shear modulus cytoplasm	G	3.65	$\left[\text{Pa}\right]$
Bulk modulus nucleus	$\kappa$	25.641	$\left[\text{Pa}\right]$
Shear modulus nucleus	G	7.299	$\left[\text{Pa}\right]$
Cell initial radius	$r_0$	10.00	$\left[\mu \text{m}\right]$
Cell initial surface	$A_0$	1256.64	$\left[\mu {\text{m}}^2\right]$
Chemical length-scale	${\ell }_{\mathrm{chem}}$	0.2	$\left[\mu \text{m}\right]$