Table 3.

Gradients of the relationships between shear stiffness $B_{\mathit{n}\mathit{s}}$ and various LV functions in HCM and DCM at different settings

LV geometry	FE simulation settings	Gradient
		EF (%)	SV (ml)	Peak systolic pressure (mmHg)	Maximal fiber stress (kPa)
Normal	Healthy settings	− 0.160	− 0.532	− 0.492	− 0.414
HCM	Healthy settings	− 0.194	− 0.552	− 0.454	− 0.134
HCM	Healthy settings, but EDP increased from 5 to 7 mmHg	− 0.208	− 0.576	− 0.488	− 0.142
HCM	Healthy settings, but epi:endo helix angle configuration changed from − 60°:60° to − 51.4°:60o	− 0.190	− 0.546	− 0.478	− 0.130
HCM	Healthy settings, but diastolic sheetlet angle changed from 18° to 48o	− 0.562	− 1.494	− 1.488	− 0.524
HCM	Disease settings	− 0.572	− 1.508	− 1.526	− 0.556
DCM	Healthy settings	− 0.016	− 0.178	− 0.140	− 0.160
DCM	Disease settings	− 0.018	− 0.180	− 0.130	− 0.140