Table 1.
Markers of venous thromboembolism and characteristics of patients with alopecia areata and healthy controls
| Parameter | Patients with alopecia areata (n = 51) | Healthy controls (n = 26) | Statistical significance |
|---|---|---|---|
| Thromboembolism markers | |||
| Soluble fibrin monomer complex (µg/ml), median (IQR) | 25.66 (20–34.86) | 21.46 (15.38–29.48) | < 0.05 |
| Thrombin–antithrombin complex (pg/ml), median (IQR) | 5690 (4177–9617) | 7417.50 (4453–12,530) | 0.42 |
| Prothrombin fragment 1 + 2 (pg/ml), median (IQR) | 70150 (43720–86,070) | 38620 (31550–58840) | < 0.001 |
| Demographic and clinical data | |||
| Age (years), median (IQR) | 38 (29–54) | 37 (29–51) | 0.8 |
| Sex (men), n (%) | 16 (31%) | 8 (31%) | 0.95 |
| BMI (kg/m2), median (IQR) | 24.38 (21.51–28.09) | 22.7 (20.43–26.12) | 0.15 |
| Age at the first episode of alopecia (years), mean (range) | 32 (3–71) | NA | |
| Number of episodes of hair loss, n (range) | 4 (1–30) | NA | |
| Duration of the present episode of alopecia (months), mean (range) | 34 (1–300) | NA | |
| SALT, mean (range) | 42 (1–100) | NA | |
| Activity of the disease, n (%) | |||
| Active | 21 (41%) | NA | |
| Stable | 22 (43%) | ||
| Remitting | 8 (16%) | ||