Table 1.
Material and reagent list used in the radiosynthesis of [18F]FSPG via TRACERlab™ FXFN module
| aItem # | Reagents or consumables |
|---|---|
| 1 | Potassium carbonate/kryptofix QMA elution solution, 0.6 mL |
| 2 | Anhydrous acetonitrile, 0.6 mL |
| 3 | FSPG precursor, 6 mg dissolved in 1.0 mL anhydrous acetonitrile |
| 4 | 1M H2SO4, 2.0 mL |
| 5 | 4M NaOH, 1.5 mL |
| 6 | 1M H2SO4, 4.0 mL |
| 7 | Sterile water for injection (SWI), 15.0 mL |
| 8 | bPhosphate buffer solution, 20.0 mL |
| 9 | Pre-conditioned QMA light SepPak cartridge, 1 cartridge |
| 10 | cOasis® MCX cartridge/glass membrane filter assembly, 1 set |
| 11 | dAlumina N plus long cartridge/Superclean™ ENVI-Carb™ assembly, 1 set |
| 12 | Final Product vial, 1 vial |
aItems designation and position are indicated in Fig. 3
bFormulation of phosphate buffer solution is specified in the Materials and methods “General” section
cIllustration of the Oasis® MCX cartridge/glass membrane filter assembly is shown in Fig. 5a
dIllustration of the Alumina N Cartridge/Superclean™ ENVI-Carb™ assembly is shown in Fig. 5b