Table 3.
Toxicity prediction results for the selected 5 natural compounds as calculated using online tool ProTox-II (Banerjee et al. 2018)
| No | Natural compound | Predicated LD50 (mg/kg) | Predicted toxicity class | Average similarity (%) | Prediction accuracy (%) | Toxicity |
|---|---|---|---|---|---|---|
| 1 | 435 | 800 | 4 | 47.51 | 54.26 | Hepatotoxicity, Carcinogenicity, Mutagenicity, Aryl hydrocarbon receptor (AhR) |
| 2 | 436 | 500 | 4 | 46 | 54.26 | Carcinogenicity, Mutagenicity, Cytotoxicity |
| 3 | 1812 | 200 | 3 | 56.69 | 67.38 | Hepatotoxicity, Immunotoxicity, Mutagenicity |
| 4 | 2584 | 1000 | 4 | 61.82 | 68.07 | None |
| 5 | 2545 | 1600 | 4 | 59.22 | 67.38 | Immunotoxicity |