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. 2022 Dec 13;37(11):2335–2343. doi: 10.1038/s41433-022-02346-2

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© The Author(s), under exclusive licence to The Royal College of Ophthalmologists 2022. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 2 — Cost-effectiveness acceptability curve for the genetic screening programme in Australia (a) and the UK (b); Tornado diagram demonstrating deterministic one-way sensitivity analysis for Australia (c) and the UK (d) models. The probability that the screening programme is cost-effective at different willingness to pay (WTP) thresholds for Australia (a) and the UK (b) models. The programme was defined as cost-effective if ICER is less than the WTP threshold, which was set at AU$54,808 in Australia and £30,000 in the UK. Costs are given in Australian dollars in c and British pounds in d.