Fig. 2. Animal experimental design and bony union assessment.
a Schematic illustration of femoral bone transport over the IM implant (IMI) in a rat femur. b Photographs of the femoral specimens harvested on post operation day 34 (POD34) or POD55. The rats were subjected to bone transport only (BLK) or implantation of collagen sponge (CS) preabsorbed with BMP-2 (2 μg). Other rats were treated with IM implants only (IMI) or implants which were loaded with 0.5 μg (IMI + B0.5), 2 μg (IMI + B2) or 6 μg (IMI + B6) BMP-2. Blue and yellow arrows point to the docking sites or regenerate sites. c Bony union rates on POD34 determined by imaging (n = 8). d Bony union rates on POD55 (n = 8). Union rates data are presented as percentages. Source data are provided as a Source data file.
