Table 2.
Characteristics of geographic atrophy ROIs by predominant precursor lesions.
| Group 1 Soft drusen/PED | Group 2 Mixed drusen /SDDs | Group 3 SDDs | |
|---|---|---|---|
| Number of ROIs (n) | 18 | 22 | 12 |
| mean qAF ± SD (qAF units) | 35.88 ± 12.75 | 58.13 ± 11.88 | 71.62 ± 12.12 |
| Mean area ± SD (mm2) | 4.22 ± 7.08 | 2.69 ± 3.08 | 2.72 ± 2.57 |
| GA aspect (%) | |||
| •Isolated | 61.11 | 54.54 | 33.33 |
| •Multilobular | 38.88 | 45.45 | 66.66 |
| •Foveal | 55.5 | 22.72 | 8.33 |
| •Extrafoveal | 45.5 | 77.27 | 91.66 |
| ROIs examined for BLamD (n) | 8 | 10 | 5 |
| Number of B-scans through each individual ROI | 7 | 7 | 7 |
| 7 | 16 | 9 | |
| 6 | 14 | 7 | |
| 4 | 5 | 4 | |
| 7 | 10 | 16 | |
| 40 | 13 | ||
| 10 | 18 | ||
| 7 | 34 | ||
| 15 | |||
| 7 | |||
| % of scans for each ROI with BlamD* | 0 | 43 | 100 |
| 0 | 63 | 88 | |
| 0 | 7 | 57 | |
| 25 | 0 | 100 | |
| 0 | 10 | 56 | |
| 8 | 14 | ||
| 0 | 33 | ||
| 0 | 38 | ||
| 7 | |||
| 29 | |||
BlamD basal laminar deposit, PED pigment epithelial detachment, SDD subretinal drusenoid deposit, GA Geographic atrophy, ROI region of interest, qAF quantitative autofluorescence, SD Standard deviation.
*Group ranks and all pairs of group ranks are significantly different (Kruskall–Wallis test).